Stem Cell Treatments For COPD
You have a lung disease and you have exhausted all the options your doctor has recommended. Most clinical outcomes of CODP remained reduced after 6 months of treatment, including the CRP, mMRC score, CAT score, and number of exacerbations, while the 6MWT score was slightly increased in stage D COPD patients. The two main types of COPD are chronic bronchitis and emphysema Many people with COPD have a combination of both.
In addition, they observed new mitochondria moving from the stem cells into the neighbouring damaged airway cells, restoring their function. It will also be important to deliver cells to the lung in a way that will allow them to integrate into the lining of the lung airways and air sacs to carry out their job.
Emphasis in the study of MSCs for use in COPD and other lung diseases accordingly has shifted to both understanding and exploiting their paracrine and other properties, independent of their differentiation abilities ( 17 ). This is particularly important for COPD as it is a chronic inflammatory as well as destructive disease with ongoing pulmonary and systemic inflammation even after smoking cessation.
We continue to work very hard to develop stem cell therapies to reconstitute diseased lungs, such as lungs that have been destroyed by emphysema. Fat tissue, however, can quickly and painlessly yield the needed stem cells for treatment. Chronic Bronchitis and Emphysema are considering to be COPD and the main causes are newest treatment for copd smoking, exposure to certain chemicals, bronchial hyper-reactivity and in some cases genetic factors.
GIOSTAR practice the application of stem cell therapy within the legal regulations of each country. The major cause of COPD is smoking, but it can also be caused by air pollution (including second-hand smoke), severe asthma, and repeated lung infections during childhood.
Activation of endogenous stem cells or progenitor cells to induce regeneration of the functional alveolar epithelial cells theoretically can be an alternative approach for reversing COPD. Li X, Zhang Y, Yeung SC, Liang Y, Liang X, Ding Y, et al. Mitochondrial transfer of induced pluripotent stem cell-derived mesenchymal stem cells to airway epithelial cells attenuates cigarette smoke-induced damage.